University and college students can experience depression, anxiety, stress or a combination.  The effect of physical activity on the emotional state of individuals, including students is receiving increased attention from scholars and practitioners. To better understand the relationship between physical activity and negative emotional states, a number of psychological factors need to be taken into account such as exercise tolerance and resilience. The results of the current study indicate that the level of physical activity can predict negative emotional states indirectly through exercise tolerance and resilience. The results of this study indicate regular physical activity can reduce the risk of experiencing negative emotional states, and potentially lowers the risk of students developing mental health disorders.