In contemporary society, the rising prevalence of chronic diseases, such as diabetes, cardiovascular diseases, and mental health issues poses a significant challenge to people’s quality of life and overall well-being [1]. While pharmacological, surgical, and psychological interventions offer effective treatments, their associated costs are substantial, and the global increase in individuals living with long-term health conditions amplifies the financial strain on both patients and healthcare systems [2]. Consequently, there is increasing interest and research into modifiable lifestyle factors [3,4] as promising strategies to manage chronic diseases, enhance mental health, support a return to daily activities, and improve the overall quality of life. Moreover, emerging evidence suggests that lifestyle modifications may reduce the risk of developing chronic conditions, benefiting individuals and alleviating the burden on healthcare systems. This special issue highlights the potential of modifiable lifestyle factors to promote better physical and mental health outcomes (see Fig. 1).
Feasibility and exploratory cognitive outcomes of three exercise modalities in oldest-old adults in assisted living facilities: A 24-week pilot randomized controlled trial
Tao, Y., Wang, H., Zhang, Z., Yu, Q., Heath, M., Tari, B., Taylor, A., Kramer, A. F., Erickson, K. I, Ligeza, T. S., Paas, F., Teo, W-P., Falck, R. S., Liu-Ambrose, T., Herold, F. & Zou, L. (2026). Feasibility and exploratory cognitive outcomes of three exercise modalities in oldest-old adults in assisted living facilities: A 24-week pilot randomized controlled trial. Journal of affective Disorders 408, 121913 URL